Serdecznie zapraszamy 19 czerwca 2023 r. o godzinie 12:00 na Seminarium Centrum Marka Kaca pod tytułem Towards an integrated molecular and quantitative framework for characterising integrons in environmental bacterial hosts, które wygłosi dr Qi Qin z Macquarie University w Sydney, Australia. Seminarium odbędzie się w sali D-2-43 Wydziału Fizyki, Astronomii i Informatyki Stosowanej UJ.
Abstrakt
Integrons are primarily bacterial genetic elements that play important roles in microbial adaptation. The first integrons were discovered in 1989 through their roles in disseminating antibiotic resistance. Over time, the roles of integrons beyond antibiotic resistance have become increasingly recognised. In my talk, I shall present on some of our latest findings on diverse integrons uncovered from soil- and plant-associated bacterial isolates via NanoPore long-read sequencing and the quantitative toolkit we developed to characterise these integrons and their components. It is hoped that these quantitative molecular experiments will contribute towards the development of mathematical models that explain the gene expression profiles of integrons and their evolutionary dynamics.